Mix the base: In a medium mixing bowl, add mayonnaise, apple cider vinegar, and lemon juice. Whisk until smooth and creamy.
Add flavor: Stir in horseradish, Dijon mustard, and all dry spices (salt, pepper, garlic powder, onion powder, cayenne). Mix well.
Taste and adjust: Add sugar if needed for balance. Adjust vinegar or pepper to taste.
Rest for flavor: Cover and refrigerate for 30 minutes before serving — this allows the flavors to meld beautifully.
Serve: Drizzle over grilled chicken, pork, or ribs, or use as a dip for fries and veggies.